[Wegener's granulomatosis with oral mucosal involvement as first manifestation].

نویسندگان

  • Alberto Candau
  • Borja Valenzuela
  • Alicia Dean
  • Francisco J Alamillos
چکیده

Wegener’s granulomatosis (WG) is an autoimmune disease, which particularly affects the upper respiratory pathways, lungs and kidney. Oral mucosal involvement presents in around 5%--10% of cases and may be the first disease symptom. Predominant manifestation is granulomatous gingivitis erythematous papules; mucosal necrosis and non-specific ulcers with or without impact on adjacent structures. Clinically speaking, the most characteristic lesion presents as a gingival hyperplasia of the gum, with hyperaemia and petechias on its surface which bleed when touched. Due to its appearance, it has been called ‘‘Strawberry gingiva’’. The following is a clinical case in which the granulomatous strawberry gingivitis was the first sign of WG.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Unilateral eyelid edema and mucosal involvement as the first presentations of Wegener granulomatosis

Background: Wegener granulomatosis or granulomatosis with polyangiitis is a pauci-immune small vessel vasculitis which is usually associated with anti-neutrophil cytoplasmic antibodies (ANCA) mainly in old men. This small vessel vasculitis is usually characterized by necrotizing granulomatous inflammation with multiorgan involvement. Kidneys could be involved as the main and life-threatening co...

متن کامل

Wegener Granulomatosis with Oral Involvement as Primary Manifestation: A Case Study

Introduction: Wegener Granulomatosis is a rare multisystemic disease with an unknown cause, characterized by necrotic granulomatous lesions in respiratory tract, systemic vasculitis in small arteries and veins and necrotizing glomerulonephritis. Wegener can affect any organ including kidneys, eyes or other organs but classically affects upper and lower respiratory tract. One of the rare but imp...

متن کامل

Wegener's granulomatosis: description of a case with oral manifestation.

Wegener's granulomatosis is a multisystemic granulomatous vasculitis that predominantly affects the airways and the kidneys, but may affect any organ. Otorhinolaryngological manifestations may be oral ulcers, gingival swelling or septal perforations that can cause saddle nose deformities, rhinitis, sinusitis and hearing loss. The oral ulcers usually occur when the disease is advanced. Renal inv...

متن کامل

A Case of Wegener's Granulomatosis Presenting with Unilateral Facial Nerve Palsy.

Wegener's granulomatosis or granulomatosis with polyangiitis is a necrotizing vasculitis affecting both arterioles and venules. The disease is characterized by the classical triad involving acute inflammation of the upper and lower respiratory tracts with renal involvement. However, the disease pathology can affect any organ system. This case presents Wegener's granulomatosis presenting with fa...

متن کامل

Acute pancreatitis as a rare initial manifestation of Wegener's granulomatosis. A case based review of literature.

CONTEXT Vasculitis is a known cause of pancreatitis and other gastrointestinal symptoms; however, most of these patients have medium vessel vasculitis like polyarteritis nodosa and often there are other associated conditions like hepatitis B or clinical manifestations that suggest the diagnosis. Wegener's granulomatosis is predominantly a reno-pulmonary disorder, rarely having gastrointestinal ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Acta otorrinolaringologica espanola

دوره 65 1  شماره 

صفحات  -

تاریخ انتشار 2014